PROJECTS
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Non invasive diagnosis through visible light, and calculation of fractale dimension
Our latest project is a cooperation with software experts aimed on developing a medical (device) for the status determination of several autoimmune diseases, such as MS, colitis Ulcerosa, Parkinson´s disease ...
Hypericin research
The isolation and high purification of hypericin (> 99 % HPLC) and pseudohypericin from St. John's Wort. Hypericin is an extremely interesting photodynamic active substance which accumulates selectively in tumor cells. The photoactive properties allow for many medical and photophysical application options.
Peroxidase research
We isolate peroxidases from human blood, resulting in highly purified NATIVE human Myeloperoxidase (MPO) and human Eosinophil Peroxidase(EPO). Peroxidases are responsible for the progress of chronic inflammatory and neurodegenerative diseases and fundamental targets for drug research.
Salvinorin research
Salvinorin A is a psychotropic diterpene isolated from Salvia divinorum. No other natural source for this compound has been identified nor has it been synthetically produced. It is a potent non-nitrogenous kappa opioid selective agonist and its hallucinogenic effect can be observed at single doses of 200–500 µg. With regards to Salvinorin B and Salvinorin C, no activity can be oberved. |
Relevant Publications
Hypericin – Facts About a Controversial Agent.
Kubin A, Wierrani F, Burner U, Alth G, Grünberger W.
Current Pharmaceutical Design 11 (2005) 233-253
How to make hypericin water-soluble.
Kubin A, Loew HG, Jessner G, Kolbabek H, Wierrani F.
Pharmazie 63 (2008) 263-269
Fluorescence Diagnosis of Bladder Cancer with New Water Soluble Hypericin Bound to Polyvinylpyrrolidone: PVP-Hypericin.
Kubin A, Meissner P, Wierrani F, Burner U, Bodenteich A, Pytel A, Schmeller N.
Photochemistry Photobiology 84 (2008) 1560-1563.
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